HARRISBURG, Pa. - A growing number of unfilled appointments and low uptake among nursing home workers are early signs that vaccine hesitancy is becoming an issue in Pennsylvania, prompting state officials to sound the alarm Friday and urge residents to get their COVID-19 shots as quickly as possible.After months of demand outstripping supply, vaccines from Pfizer and Moderna are more readily available, and the Wolf administration said the challenge now is to assuage the concerns of people who are reluctant to get it.Gov.