COVID-19.Published online in the journal Cell, the research coming from the lab of Dr Thirumala-Devi Kanneganti, an Indian-born researcher working at St.
Jude Children's Research Hospital in Tennessee, identified the drugs after discovering that the hyperinflammatory immune response associated with COVID-19 leads to tissue damage and multi-organ failure in mice by triggering inflammatory cell death pathways.The researchers detailed how the inflammatory cell death signaling pathway worked, which led to potential therapies to disrupt the process."Understanding the pathways and mechanism driving this inflammation is critical to develop effective treatment strategies," said Kanneganti, vice chair of the St Jude Department of.