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COVID-19 variants spread faster but grew milder over time in Ohio

China city Wuhan, China state Ohio county Cleveland covid-19 patient strain
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Cleveland Clinic researchers identified 484 unique mutations among six strains of SARS-CoV-2 isolates early in the COVID-19 pandemic, finding that the first variants were more deadly than subsequent strains and suggesting that monitoring circulating strains may help predict patient outcomes.Their study, published yesterday in JAMA Network Open, involved sequencing the viral genomes from specimens obtained from 302 COVID-19 patients at Cleveland Clinic from Mar 11 to Apr 22, 2020, and comparing them with those of the original SARS-CoV-2 strain from Wuhan, China.Infection with early virus subgroups, or clades, was associated with higher death rates than later strains (21.4% vs 5.6%). "These findings help explain persistent hospitalization yet

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COVID-19
United States
United States
Cases: 46 252 513
Deaths: 750 423
Recovered: 0
India
India
Cases: 34 321 025
Deaths: 459 652
Recovered: 0
Brazil
Brazil
Cases: 21 835 785
Deaths: 608 235
Recovered: 0
United Kingdom
United Kingdom
Cases: 9 215 683
Deaths: 141 607
Recovered: 0
Russia
Russia
Cases: 8 494 589
Deaths: 237 619
Recovered: 0
Detail statistic
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