Study shows pre-pandemic global decline in antimicrobial useAn analysis of prescribing data from more than 80 countries found that global antimicrobial consumption declined prior to the COVID-19 pandemic, researchers reported today in the Journal of Antimicrobial Chemotherapy.For the cross-sectional time-series analysis, researchers from the University of Pittsburgh and the University of Toronto obtained data on global monthly purchases of antimicrobials (antibiotics, antivirals, and antifungals) from 2014 through 2020 from the IQVIA MIDAS database, which contains monthly drug data for 84 countries.
Their aim was to evaluate antimicrobial consumption pre-pandemic and assess the impact of the World Health Organization (WHO) Global Action Plan on Antimicrobial Resistance (GAP-AMR), which was adopted in 2015 to encourage countries to develop national AMR action plans.Over the study period, the worldwide monthly antimicrobial purchase rate averaged 112.9 units per 1,000 population, with antibiotics accounting for 88.7% of antimicrobial consumption.
Prior to the pandemic, the average monthly antimicrobial consumption rate in developed countries changed by –8.4%, compared with –1.2% in developing countries.
Among countries with an AMR national action plan, all but five experienced a decline in average monthly antibiotic consumption pre-pandemic.Global antimicrobial consumption increased by 11.2% from March 2019 to March 2020.