NEW DELHI : Single-dose of Covishield vaccine elicits a stronger immunity in individuals recovered from SARS-CoV-2 infection compared with those having no prior exposure, indicated a study published in the International Journal of Infectious Diseases.The researchers enrolled over 280 healthcare workers who were vaccinated between 16 January and 5 February 2021, at AIG Hospitals, Hyderabad, for enumerating neutralizing antibodies and memory T- and B-cells.
Participants who were RT-PCR positive for SARS-CoV-2 and recovered formed the previously infected group, and participants who were RT-PCR negative formed the no prior exposure group.