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Roche bid to retool arthritis drug for COVID-19 fails

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ZURICH : Roche's attempt to retool its rheumatoid arthritis drug Actemra/RoActemra to treat patients hospitalised with severe COVID-19-related pneumonia has failed in a late-stage trial, the Swiss company said on Wednesday.Roche launched the 330-patient trial in March as it joined other pharmaceutical companies seeking to re-purpose existing medicines to fight the pandemic.The "COVACTA trial did not meet its primary end-point of improved clinical status in patients with COVID-19 associated pneumonia, or the key secondary end-point of reduced patient mortality," Roche said.The news follows an Italian study that showed the drug failed to help patients with early-stage COVID-19 pneumonia.Roche shares were little changed."For COVID-19 patients.

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