Two doses of the Pfizer/BioNTech COVID-19 vaccine were safe and 78% effective in preventing infection in pregnant women in a real-world study in Israel.Led by researchers at Maccabi Healthcare Services in Tel Aviv, the retrospective, observational study was published yesterday in JAMA.
It involved analyzing data on 15,060 women in a pregnancy registry of a large, state-mandated healthcare system who were vaccinated with a first dose from Dec 19, 2020, to Feb 28, 2021.The women were matched in a 1:1 ratio with unvaccinated pregnant women by age, gestational age, residential area, population subgroup, number of times they had given birth, and flu vaccination status (a proxy for health-seeking behavior) and followed until Apr 11, 2021.Risk