Both the Pfizer/BioNTech and AstraZeneca/Oxford University COVID-19 vaccines significantly reduce severe illness, hospitalization, and death in older adults and offer protection against the B117 variant, suggests a real-world, observational, non–peer-reviewed study from the United Kingdom.The study, led by researchers from Public Health England (PHE) and published yesterday on a preprint server, compared the rate of vaccination in symptomatic people older than 70 who tested positive for coronavirus with that of those who weren't vaccinated from Dec 8, 2020, to Feb 19, 2021.
A total of 44,590 participants with available vaccination data tested positive for COVID-19, while 112,340 tested negative.The investigators found that one dose of the