People who had a severe allergic reaction to their first dose of mRNA COVID-19 vaccine had no issues after their second dose, according to a retrospective multicenter US study today in JAMA Internal Medicine.Allergic reactions are estimated to occur in up to 2% of people after their first mRNA COVID-19 vaccine dose, with anaphylaxis reported in as many as 2.5 per 10,000 vaccinees.
Anaphylaxis is a severe and potentially deadly systemic allergic reaction.From Jan 1 to Mar 31, a team led by researchers at Massachusetts General Hospital (MGH) analyzed data from 189 people who had sought care for allergic reactions within 4 hours after their first dose of the Pfizer/BioNTech or Moderna mRNA COVID-19.20% have mild reactions to second doseThe