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Study says dogs 97% sensitive at detecting COVID-19 in patientsCompared with reverse-transcription polymerase chain reaction (RT-PCR) testing, dogs can detect COVID-19 infections via scent with high sensitivity (97%)—though lower specificity (91%)—even when patients are asymptomatic, according to a study in PLOS One yesterday.Scientists in Paris collected nasopharyngeal, saliva, and sweat samples (from participants' armpits) from 335 outpatients, 143 of whom had COVID-like symptoms and 192 of whom did not.

Of the 335, 109 patients tested positive for COVID-19 via RT-PCR and 226 tested negative. Of the 109 volunteers with lab-confirmed COVID-19, 78 had symptoms and 31 did not.Trained dogs correctly identified 106 of the 109 COVID-positive patients and 206 of the 226 COVID-negative patients.

That translates to an overall sensitivity of 97% (95% confidence interval [CI], 92% to 99%), which reached 100% (95% CI, 89% to 100%) in asymptomatic patients compared with RT-PCR from nasopharyngeal swabs.

The dogs' specificity was 91% (95% CI, 72% to 91%), reaching 94% (95% CI, 90% to 97%) in asymptomatic patients. That compares with 84% sensitivity and 97% specificity for nasopharyngeal antigen testing.The study authors conclude, "Our results show the excellent sensitivity of SARS-CoV-2 detection by dogs using nasopharyngeal RT-PCR as the reference for comparison.

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