More than 4,000 cases of coronavirus have been recorded in Greater Manchester in a single week.The total number of cases has gone up by 4,322 in the seven days to September 21.Every single borough across the region remains on red alert.Bolton still has the highest infection rate in the country with 218.4 cases per 100,000 people in the week ending September 21.In Bury, Manchester, Oldham, Rochdale, Salford, Tameside and Wigan the infection rates are still well above 100.Trafford has the lowest rate in the region with 71.2 cases per 100,000 people.In recent days, infection rates have continued to climb in both Stockport and Wigan.As such, local leaders are expected to imposing tougher restrictions in the two boroughs.Ministers held their.