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Mix and match of Covid-19 vaccine for booster shots unlikely to be allowed: Report

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PTI, quoting sources, on Thursday. This comes in light of a recent study by the Christian Medical College (CMC) Vellore, which showed that a booster dose of Covishield after primary vaccination with Covaxin gives 6 to 10 times higher antibody levels.

However, similar results for not observed when Covaxin was given as a booster after two Covishield doses. According to PTI, the Covid Working Group of NTAGI has reviewed the findings of the study. "Considering programmatic challenges the matter would now be discussed in the NTAGI standing technical sub-committee meeting for a final recommendation," a source was quoted as saying.

As of now, mixing of Covid-19 vaccines is not allowed in the country, which means the precaution dose is of the same vaccine as the first and second doses.  Biological E seeks Corbevax approval as booster This comes after Hyderabad-based Biological E on 4 May submitted an application to India's drug regulator, seeking emergency use authorisation for its Covid-19 vaccine Corbevax as a booster dose for adults who have been given two doses of either Covishield or Covaxin.

According to the EUA application submitted to DCGI, Biological E in a phase-3 placebo-controlled clinical study has evaluated the safety and immunogenicity of Corbevax as a single-dose booster in Covid-negative adults vaccinated with Covishield or Covaxin.

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