Packet of pills. (Photo by SSPL/Getty Images)LOS ANGELES - There may be a male birth control pill available soon as scientists presented promising new findings on a contraceptive that reportedly has proven safe and effective on mice.
Clinical trials in humans are set to occur as early as this year.According to researchers from the University of Minnesota, the pill did not target testosterone and it even cut the risk of unwanted side effects like weight gain and depression. "Most female birth control pills work on the female sex hormones," said Abdullah al Noman in a presentation posted to YouTube on March 23. "Targeting the male sex hormone leads to a lot of side effects such as weight gain, depression and increased risk of cardiovascular diseases." He continued, "Men are less willing to take a birth control pill that has significant side effects.
That’s why we are targeting a non-hormonal pathway to developing a male birth control pill."The contraceptive targets a protein that helps form a type of vitamin that helps sperm formation.
But researchers found that knocking out this specific protein made the mice infertile. The pill dramatically reduced the sperm count of the mice, preventing pregnancy by 99 percent without causing any observable side effects.Once taken off the pill, the male mice became fertile roughly four to six weeks later."Of course, you have to be careful with this analysis because they are mice and not humans, but nevertheless the effect was very, very promising," said Gunda Georg, Ph.D., one of the lead researchers.