Coronavirus restrictions were reimposed across much of Italy today, while Ireland and the Netherlands became the latest countries to suspend AstraZeneca's Covid-19 shots over blood clot fears despite the firm and the WHO insisting there is no risk.
More than 350 million vaccine doses have been administered globally so far, and the AstraZeneca shot - among the cheapest available - is crucial to roll-outs in poorer parts of the world.
Despite immunisation programmes gathering pace, surges in infections remain a threat and Italian authorities reimposed restrictions on three-quarters of the country until 6 April to suppress an outbreak fuelled by the variant first detected in Britain.