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COVID-19 Scan for May 12, 2022

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Moderna vaccine up to 88% effective against COVID in kids 6 to 11 yearsEstimated effectiveness of the Moderna COVID-19 vaccine against infection in children 6 to 11 years old was 88% at least 14 days after the first dose amid the Delta variant surge, before the emergence of Omicron, finds an interim analysis from a phase 2/3 clinical trial.Vanderbilt University investigators led the study, which was conducted at 79 US and 8 Canadian sites and published yesterday in the New England Journal of Medicine (NEJM).In part 1, the team randomly assigned 751 children aged 6 to 11 to receive 50- or 100-microgram (μg) doses of the vaccine from March to August 2021.

After evaluation of safety and immunogenicity, the 50-μg dose was chosen for part 2 of the trial.In part 2, 4,016 children were randomly assigned in a 3:1 ratio to receive either two 50-μg vaccine doses or a placebo 28 days apart.

Follow-up was a median of 82 days.The vaccine was tied to primarily low-grade, limited adverse events such as injection-site pain, headache, and fatigue.

No serious adverse events, multisystem inflammatory syndrome in children, myocarditis, or pericarditis were reported.One month after dose two, concentrations of SARS-CoV-2 neutralizing antibodies in children given a 50-μg dose were more than twice as high as those in adults 18 to 25 years given a 100-μg dose in a related phase 3 trial.

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Housing affordability in Ontario has eroded faster than any province amid COVID-19: report
Housing affordability in Ontario has eroded at a rate not seen in half a century over the course of the COVID-19 pandemic, a new report suggests, while home prices skyrocketed by 44 per cent across Doug Ford’s premiership.The new report by Generation Squeeze found that with current home prices, a new homebuyer would have to work full-time for nearly 22 years to save up enough money for a 20 per cent down payment on a home — up from 15 years in late 2019.“Ontario has just completely lost control of housing,” said Paul Kershaw, an associate professor at the University of British Columbia and the founder of Generation Squeeze, which studies housing affordability and standard of living across Canada.“We’ve never seen anything like this before in any province at any time in the last 50 years.” ‘I’ll never be able to afford property’: Housing costs key issue for Ontario voters The report, citing Canadian Real Estate Association data, found the average price for a home in Ontario rose to $871,688 by 2021, up 44 per cent from the inflation-adjusted price in 2018 — the year Ford was sworn in as premier.Meanwhile, wages have stagnated, particularly for the typical 25-to-34-year-old, which the report argues has led to “lost work” for those trying to save for a down payment.Over the first two years of the pandemic, Kershaw says those young Ontario residents have lost the value of six years of work that would otherwise be put toward home ownership.
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