Latest figures show there are 260 people with Covid-19 being treated in hospitals, down 87% from the peak on 18 January when 2,020 people with the disease were hospitalised.
There are 58 patients with Covid-19 in intensive care units, a 73% reduction since 24 January, when 221 patients with coronavirus were in ICUs.
It comes after Health Service Executive CEO Paul Reid said Ireland's vaccination programme was in a "new phase". In a post on Twitter yesterday, he said: "Huge thanks to all involved in vaccinations this weekend.
Best day ever." He said 30,000 vaccinations were carried out on Good Friday while over 120,000 jabs were administered last week - "our highest ever".